探討基因、細胞與數學的關係

2018年7月31日

香港城市大學（城大）高等研究院於7月舉辦了「基因、細胞及數學擴展研討會」，廣邀多位來自不同領域的知名學者到城大，就數學、電腦科學、細胞生物學、人類蛋白質體學和人類遺傳學跨學科研究進行為期一個月的深入交流。

是次擴展研討會由城大高等研究院資深院士及菲爾茲獎及沃爾夫數學獎得主
Stephen Smale教授領導，與美國密歇根大學Indika Rajapakse教授合辦。今年的擴展研討會是2016年「基因與染色體研討會」的延續，目的是繼續匯聚國際專家就基因組排列研究交換意見，深入了解基因功能、疾病以及染色體的相互作用及與數學的關係。

於首個討論環節上，高等研究院資深院士及菲爾茲獎及沃爾夫數學獎得主
Stephen Smale教授發表題為「Beating in Unison」的演講。

美國密歇根大學Indika Rajapakse教授發表題為「Algorithm for Cellular Reprogramming」的演講。

一眾講者於講座後仍繼續討論講題、互相交流己見。

擴展研討會有10個討論環節，共18場講座，吸引了跨學科人士的興趣，接近400名學者及學生參與。其中對基因、細胞與數學的最新趨勢和發展展出深入探討，演講題目包括 (只有英文版本)：

Folding of Proteins and RNA Using the Quantum Topology of Moduli Spaces by Prof. Jørgen ANDERSEN, Aarhus University, Denmark
The Emergence of Next Generation Pharmacogenomics Science Enabled by the 4D Nucleome, Patient Data, and Machine Learning Methods by Dr. Brian ATHEY, University of Michigan, USA
I. Neural Network Capacity & II. Systems Biology of Circadian Rhythms by Prof. Pierre BALDI, University of California, USA
The Role of Heteroclinic Trajectories in Biological Modeling by Prof. Roger BROCKETT, Harvard University, USA
GATA3 Regulates Multiple Aspects of Thymocyte Development by Prof. James Douglas ENGEL, University of Michigan Medical School, USA
Geometric Aspects of the Dynamics and Diagnosis of Cardiac Arrhythmias by Prof. Leon GLASS, McGill University, Canada
Model-Free Network Control by Prof. Gemunu GUNARATNE, University of Houston, USA
Network Inference from Multimodal Genomics by Prof. Alfred HERO, University of Michigan, USA
Control of Growth, Form and Scale in Biology by Prof. Arthur LANDER, University of California, Irvine, USA
Protein Structures: Space and Dimension by Dr. Shuai Cheng LI, City University of Hong Kong, Hong Kong
Genomics of Human Adipose Tissue Macrophages in Obesity by Dr. Lindsey MUIR, University of Michigan, USA
Computational and Bioinformatic Innovations in Proteogenomics: Predicting Functions of Unannotated Proteins and Facilitating Identification of Missing Proteins by Prof. Gilbert OMENN, University of Michigan, USA
Algorithm for Cellular Reprogramming by Prof. Indika RAJAPAKSE, University of Michigan, USA
Genome and Transcriptome Dynamics in Cancer Development by Dr. Thomas RIED, National Cancer Institute, USA
Beating in Unison by Prof. Stephen SMALE, City University of Hong Kong, Hong Kong
Discovering Multiple Levels of Regulatory Networks by Prof. Gary STORMO, Washington University in St. Louis, USA
Some Applications with Medical Data by Dr. Michael XUAN, UniData Technology, China
Localization of Heterogeneous Disease Features in Medical Imaging by Prof. Yuan YAO, The Hong Kong University of Science and Technology, Hong Kong

歡迎瀏覽講座視頻及簡報。

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